The epithermal neutron beam for BNCT under construction at TAPIRO: Physics

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Epithermal Neutron Beam Generator Design for Bnct

BNCT is a radiotherapy modality based on the neutron capture and fission reactions that occur when boron-10 is irradiated by thermal neutrons. This reaction generates alpha and lithium that produce high density of ionizations in close to the reaction site. The concept provides high absorbed doses into the cancerous cells preserving the adjacent healthy tissues. Nowadays, the available neutron s...

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LNL Annual Report 2004

In the framework of the Italian BNCT research program, the low-power (5 kW), fast-flux, TAPIRO research reactor, located at the ENEA Casaccia Centre near Rome, is foreseen to be implemented as the national facility devoted to supply an epithermal neutron beam required for malignant brain tumor treatment[1]. The feasibility to provide both thermal and epithermal suitable neutron beams in the mai...

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A new TEPC for BNCT: microdosimetric measurements at the thermal column of the TAPIRO reactor

Boron Neutron Capture Therapy (BNCT) is a rather innovative cancer radiotherapy; at present it is object of increasing interest especially for treatment of those tumors where conventional therapy gives not satisfactory results (Glioblastoma and Malignant Melanoma). The therapy takes advantage of both chemical and physical aspects B: the possibility of selectively accumulating in tumor tissue th...

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An Epithermal Neutron Source for BNCT Based on an ESQ - Accelerator

An accelerator-based BNCT facility is under development at the Lawrence Berkeley National Laboratory. Neutrons will be produced via the 7Li(p,n) reaction at proton energies of about 2.5 MeV with subsequent moderation and filtering for shaping epithermal neutron beams for BNCT. Moderator, filter, and shielding assemblies have been modeled using MCNP. Head-phantom dose distributions have been cal...

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Optimization of the epithermal neutron beam for Boron Neutron Capture Therapy at the Brookhaven Medical Research Reactor.

The use of epithermal neutron beam in clinical trials of Boron Neutron Capture Therapy for patients with malignant brain tumors had been carried out for half a decade at the Brookhaven's Medical Reactor. The decision to permanently close this reactor in 2000 cut short the efforts to implement a new conceptual design to optimize this beam in preparation for use with possible new BNCT protocols. ...

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ژورنال

عنوان ژورنال: Journal of Physics: Conference Series

سال: 2006

ISSN: 1742-6588,1742-6596

DOI: 10.1088/1742-6596/41/1/018